Innovation
New ways to make measurements
in the life sciences!

BioPAL is focused on developing and
commercializing novel tools for the life science and biomedical communities. Most of our products and technology platforms can be found nowhere else.
Kidney Diagnostic
BioPAL offers immunoassay kits to measure
the renal clearance of ideal filtration markers
to obtain an accurate GFR or RBF measurement.

• Inulin GFR kits

• Iohexol GFR kits

• Gd-DOTA GFR kits and Gd-DTPA GFR kits

• Iodohippurate RBF kits
MRI Contrast Agents
BioPAL is a leading provider of novel MRI contrast
reagents directed toward the needs of the life
science community.

• Gadolinium products - T1 imaging agents

• Iron products - T2 imaging agents
Neutron Activation Analysis
BioPAL is the first company to develop and provide
in vivo diagnostic products based on NA technology
as the readout system.

• Microspheres

• Nanoparticles

• Protein labeling kits

Gadolinium-Labeled Albumin

Technical Information

Galbumin™ is gadolinium-labeled albumin bottled at a concentration of 25 mg/ml or at a concentration of 100 mg/ml. There are approximately 10 to 15 gadolinium atoms per albumin unit and the molecular weight of the product is ~ 74k Da.

In addition, BioPAL also provides several additional Galbumin products: Trackable Galbumin™ and Glowing Galbumin™. Trackable Galbumin is gadolinium-labeled albumin laced with europium to permit tracking via BioPAL's neutron activation service. Glowing Galbumin is gadolinium-labeled albumin that is co-labeled with FITC or Rhodamine B for fluorescent imaging.

FOR RESEARCH USE ONLY.
NOT FOR USE IN DIAGNOSTIC PROCEDURES.

BioPAL offers a full line of magnetic resonance imaging (MRI) gadolinium contrast imaging agents for sale. Gadolinium labeled albumin is used for vascular MRI imaging. Gd-albium can be used for preclinical imaging and imaging research.

Galbumin™

gadolinium albumin for mri contrast imaging

A = 2mmol Gado-DTPA

B = Water

C = 0.037 mmol Galbumin

D = 0.37 mmol Galbumin

E = 1.84 mmol Galbumin

F = 3.68 mmol Galbumin

The figure was generated using Spin Echo (SE) sequence with TR/TE = 100/14, images of gadolinium labeled solutions in microtubes were obtained. The average signal intensity within a region-of-interest (ROI) is as follows: A=106, B=9, C=16, D=38, E=90, F=94. The background intensity measured is 0.7.

Published References

The Product

One ml of Galbumin, Trackable Galbumin, or Glowing Galbumin is packaged in a 2 ml sealed serum bottles at a concentration of 25 mg/ml. One ml of concentrated Galbumin is packaged in a 2 ml sealed serum bottles at 100 mg/ml. Applications include vascular imaging and injection and injection-site visualization. Suggested starting dose for rats and mice is 2-4 ml/kg.

Researchers may order Galbumin™ products online using the add-to-cart button below. Alternatively, researchers can phone, fax or e-mail a purchasing request to BioPAL. These instructions can be found on the main navigation bar above.

Cat. No.	Product Name	Price (US)	MSDS
P-00P01	Galbumin™	$135.00
P-00P01-100	Concentrated Galbumin™	$600.00
P-00PZ01	Glowing Galbumin™ - Fluorescein	$175.00
P-00PY01	Glowing Galbumin™ - Rhodamine B	$175.00

Gadolinium-labeled albumin and fluorescent-labeled albumin call galbumin for mri preclinical imaging applications used as blood pooling agents and for vascular imaging agents and probes.

BioPAL, Inc. • 80 Webster Street Worcester, MA 01603 • TEL: 508-770-1190 • FAX: 508-770-1191 • e-mail: cs@BioPAL.com