Innovation
New ways to make measurements
in the life sciences!

BioPAL is focused on developing and
commercializing novel tools for the life science and biomedical communities. Most of our products and technology platforms can be found nowhere else.
Kidney Diagnostic
BioPAL offers immunoassay kits to measure
the renal clearance of ideal filtration markers
to obtain an accurate GFR or RBF measurement.

• Inulin GFR kits

• Iohexol GFR kits

• Gd-DOTA GFR kits and Gd-DTPA GFR kits

• Iodohippurate RBF kits
MRI Contrast Agents
BioPAL is a leading provider of novel MRI contrast
reagents directed toward the needs of the life
science community.

• Gadolinium products - T1 imaging agents

• Iron products - T2 imaging agents
Neutron Activation Analysis
BioPAL is the first company to develop and provide
in vivo diagnostic products based on NA technology
as the readout system.

• Microspheres

• Nanoparticles

• Protein labeling kits

Effective Renal Blood Flow (FIT-RBF) Test

Technical Information

Based on functional immunoassay technology (FIT™), FIT-RBF™ kits provide a superior analytical method to measure effective renal blood flow. BioPAL's FIT-RBF test, whose analytical segment uses immunoassay, overcomes all the major limitations associated with current analytical technology. The presence of a GFR marker, such as Inulin, Iohexol, Gd-DTPA or Gd-DOTA, in the sample will not affect the accuracy of the FIT-RBF measurement. Therefore, researchers can simultaneously obtain a GFR and RBF measurement in the same subject using BioPAL's FIT kits.

Glomerular filtration rate (GFR) is the measure of the total volume of plasma actually filtered through the glomerulus per unit of time, while the effective renal blood flow (RBF) is the measure of the total volume of plasma passing through the kidney per unit time. These two measurements can be obtained simultaneously using FIT and allows researchers the ability to calculate the renal filtration fraction (FF). The FF is the ratio of the GFR and RBF and represents the amount of plasma/blood flowing through the kidney that is actually being filtered. These are three fundamental measurements in the field of nephrology.